Puberty is a critical process characterized by several physical and psychological changes that culminate in the achievement of sexual maturation and fertility.The onset of puberty depends on several incompletely understood mechanisms that certainly involve gonadotropin-releasing hormone (GnRH) and its effects on the pituitary gland.The role of mako
Clear cell renal cell cancer (ccRCC) is a tumor of high malignancy, which can escape apoptosis.The tumor protein p53-inducible nuclear protein 2 (TP53INP2), known as where to buy powdered food coloring an autophagy protein, is the essential part for autophagosome formation and sensitizes cells to apoptosis.Our study is aimed at exploring the role o
Objective: to provide evidence-based up-to-date recommendations for the management of patients with a definite diagnosis of polymyalgia rheumatica (PMR).Methods: A systematic literature review was performed to find the existing clinical practice guidelines (CPGs) on PMR and the framework of the Guidelines International Network Adaptation Working Gr